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Probiotic/Prebiotic Digestive Support

Symbiotic supports optimum digestive function and immune health by helping maintain a healthy bacterial population throughout the gastrointestinal tract. This proprietary blend of probiotics and prebiotics is beneficial for horses who have difficulty maintaining weight, are susceptible to hindgut issues or loose manure, and those at risk for gastric upset due to stress, traveling, training, or changes in their diet or environment.  

As hindgut fermenters, horses utilize beneficial bacteria and other microorganisms to help digest fiber. The fermentation of fiber in the hindgut produces volatile fatty acids utilized for energy and synthesis of B vitamins. 

Most live probiotics die during processing and packaging, long before reaching your horse. Symbiotic, however, contains Saccharomyces Boulardii, a live microorganism that does not require refrigeration and can withstand GI stresses to colonize the hindgut. Together with TruEquine™ Yeast Culture, this combination of live probiotics and prebiotics helps beneficial bacteria flourish, and supports a tight intestinal lining that filters out toxins that could be absorbed into the blood stream via “leaky gut.”

Saccharomyces Boulardii withstands stress of gastric transit to target hindgut

Supports a healthy environment for stomach and intestinal mucosa

Reestablishes gut function after medications have disrupted balance of beneficial microbes 

TruEquine™ Yeast Culture (Saccharomyces Cerevisiae) supports digestion and normalization of gut microflora

Beta glucans moderate release of sugars into bloodstream 

Repairs damage to intestinal lining caused by NSAIDS to restore “leaky gut” to normal permeability levels

What's Inside
  • TruEquine™ Yeast Culture

    TruEquine™ Yeast Culture

  • Saccharomyces Boulardii

    Saccharomyces Boulardii

  • Apple Pectin

    Apple Pectin

  • Aspergillus Oryzae

    Aspergillus Oryzae

  • Beet Pulp

    Beet Pulp

  • Dehydrated Cabbage

    Dehydrated Cabbage

  • Fenugreek Seed

    Fenugreek Seed

Horse Show Safe

Contains no prohibited substances

Lab Tested

Drug screen by FEI recognized laboratory


Picky eater approved

Key Ingredients

  • TruEquine™ Yeast Culture
  • Aspergillus Oryzae
  • Fenugreek Seed
  • Saccharomyces Boulardii
  • Dehydrated Cabbage
  • Beet Pulp
  • Apple Pectin
Product Label


22.22g (2 scoops - 1AM/1PM)

1 scoop AM


1 scoop PM



Small Bag (1.48lbs)

120 DAYS

Large Bag (5.92lbs)


Proprietary blend of TruEquine™ Yeast Culture, aspergillus oryzae fermentation extract, saccharomyces boulardii, dehydrated cabbage, fenugreek seed, beet pulp, apple pectin


One scoop = 11.11g.  Best results obtained with continued use.  To maximize freshness, store in a cool dry place with bag closed when not in use. Serving sizes may be doubled during times of additional stress or for extra support.

(<500lbs): Administer 1 scoop daily.
(500-1,200lb): Administer 2 scoops daily.
(>1,200lb): Administer 2.5 scoops daily.


  • Safe use in pregnant animals or animals intended for breeding has not been proven.
  • If animal’s condition worsens or does not improve, stop product administration and consult your veterinarian.


  • For animal use only.
  • Keep out of reach of children.
  • In case of accidental overdose, contact a health professional immediately.
  • Should not be used for animals intended for human consumption.

Equine Elixirs’ liability for use of this product shall not exceed this product’s purchase price.  Equine Elixirs shall not be liable for any consequential or incidental damages resulting from use of this product.


Equine Elixirs, Inc.
Palm Beach, FL 33480
[email protected]

Research and Testing

Comprehensive prohibited substance screen performed by LGC Science, Inc., an FEI recognized laboratory, and the laboratory that performed the FEI drug testing for the 2016 Rio Olympics. For more information visit the following sites:

LGC Performs FEI Drug Testing for Rio Olympics

FEI Laboratories

Aspergillus Orzaey 

Beharka, A.A. 1993.  Effect of Aspergillus Orzaey fermentation extract on in vitro fiber degradation.  J. of Dairy Sc. Volume 76, Issue 3, 812-18. 


D. Goodwin, H.P.B. Davidson, P. Harris. Selection and acceptance of flavours in concentrate diets for stabled horses. Applied Animal Behaviour Science , Volume 95 , Issue 3 , 223 - 232. 

Jette L, Harvey L, Eugeni K, Levens N. 4-Hydroxyisoleucine: a plant-derived treatment for metabolic syndrome. Curr Opin Investig Drugs. 2009 Apr;10(4):353-8. 

Platel K, Srinivasan K. Influence of dietary spices or their active principles on digestive enzymes of small intestinal mucosa in rats. Int J Food Sci Nutr. 1996 Jan;47(1):55-9. 

FOS (Fructooligosaccharides) 

Johnson ACB, Rossow HA. Effects of two equine digestive aid supplements on hindgut health. Translational Animal Science. 2019 Jan;3(1):340-9. 

Respondek F, Goachet AG, Julliand V. Effects of dietary short-chain fructooligosaccharides on the intestinal microflora of horses subjected to a sudden change in diet. J Anim Sci. 2008 Feb;86(2):316-23. 

Respondek F, Myers K, Smith TL, et al. Dietary supplementation with short-chain fructo-oligosaccharides improves insulin sensitivity in obese horses. J Anim Sci. 2011 Jan;89(1):77-83. 


Harris RC, Harris PA, Routledge NB, et al. Plasma glutamine concentrations in the horse following feeding and oral glutamine supplementation, Equine Vet J Suppl. 2006 Aug;(36):637-42. 

Roth E. Nonnutritive effects of glutamine. J Nutr. 2008 Oct;138(10):2025S-2031S. 

MOS (Mannanoligosaccharides) 

Johnson ACB, Rossow HA. Effects of two equine digestive aid supplements on hindgut health. Translational Animal Science. 2019 Jan;3(1):340-9. 

Koke K, Reddish JM, Share E, Cole K. Effects of dietary yeast supplementation on serum IgG(T) concentrations in Quarter Horse mares. J Eq Vet Sci. 2013 May;33(5):396. 


Ferrucci F, Zucca E, Croci C, et al. Treatment of gastric ulceration in 10 standardbred racehorses with a pectin-lecithin complex. Vet Rec. 2003 May 31;152(22):679-81. 

Venner M, Lauffs S, Deegan E. Treatment of gastric lesions in horses with pectin-lecithin complex. Equine Vet J Suppl. 1999 Apr;(29):91-6. 

Saccharomyces Boulardii 

Desrochers, A. M., B. A. Dolente, M. F. Roy, R. Boston, S. Carlisle. 2005. Efficacy of Saccharomyces boulardii for treatment of horses with acute enterocolitis. J. Am. Vet. Med. Assoc. 227(6):954-959. doi: 10.2460/javma.2005.227.954 

Czerucka, D., and P. Rampal. 2019. Diversity of Saccharomyces boulardii CNCM I-745 mechanisms of action against intestinal infections 

More, M. I., and A. Swidsinski. 2015. Saccharomyces boulardii CNCM I-745 supports regeneration of the intestinal microbiota after diarrheic dysbiosis – a review. Clin. Exp. Gastroenterol. 8:237-255. doi: 10.2147/CEG.S85574. 

Rodriguez-Nogales, A., F. Algieri, J. Garrido-Mesa, T. Vezza, M. P. Utrilla, N. Chueca, F. Garcia, M. E. Rodriguez-Cabezas, and J. Galvez. 2018. Intestinal anti-inflammatory effect of the probiotic Saccharomyces boulardii in DSS-induced colitis in mice: Impact on microRNAs expression and gut microbiota composition. J. Nutr. Biochem. 61:129-139. doi: 10.1016/j.jnutbio.2018.08.005.  

Saccharomyces Cerevisiae 

J Anim Sci. 2002 Oct;80(10):2600-9. Effect of a preparation of Saccharomyces cerevisiae on microbial profiles and fermentation patterns in the large intestine of horses fed a high fiber or a high starch diet. Medina B1, Girard ID, Jacotot E, Julliand V 

J Anim Sci. 2009 Sep;87(9):2844-52. doi: 10.2527/jas.2008-1602. Epub 2009 May 22. Effect of live yeast culture supplementation on hindgut microbial communities and their polysaccharidase and glycoside hydrolase activities in horses fed a high-fiber or high-starch diet. Jouany JP1, Medina B, Bertin G, Julliand V. 

TruEquine Diamond V® Yeast 

Martinez R, Leatherwood J, Valigura H. Responses to an intra-articular lipopolysaccharide challenge following dietary supplementation of Saccharomyces cerevisiae fermentation product in young horses. J Eq Vet Sci. 2019 May;76:80. 

Valigura H, Leatherwood J, Martinez R. Dietary supplementation of Saccharomyces cerevisiae fermentation product attenuates exercise-induced stress markers in young horses. J Eq Vet Sci. 2019 May;76:48 

Why the long face? We have answers to your questions right here.


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What makes Symbiotic different from other probiotics?

Most probiotics are white powders where the bacteria died during processing and packaging, or otherwise die upon reaching the acidic environment of the stomach. Symbiotic uses a strain of yeast that does not require refrigeration, survives packaging, and that is proven to withstand the stresses of GI transit to successfully colonize the hindgut. Symbiotic contains other yeasts and forage based prebiotics that horses love the smell and taste of.


Why do people supplement with prebiotics and probiotics?

Often times, the delicate balance of beneficial bacteria in the GI tract is disrupted (i.e. due to medications, stress, illness, changes in feed or environment) and this can lead to various gastric issues. Maintaining a healthy population of beneficial bacteria while keeping the bad bacteria at bay is essential for proper nutrient absorption and immune health.


What are prebiotics and probiotics?

Probiotics are beneficial bacteria in your horse's GI tract that assist with digestion.  Prebiotics are the food source for the beneficial bacteria.  


Can I use Symbiotic with Ulceraser?

Yes!  In fact they are designed to complement one another by focusing on the gastric and colonic needs of your horse.


What type of horses benefit from Symbiotic?

All of them! To name just a few: senior horses needing improved nutrient digestibility and absorption to help maintain weight; foals and young growing horses that need to establish beneficial bacteria throughout the GI tract; performance horses susceptible to hindgut disturbance caused by sugar and starch content of large grain meals needed to meet their energy requirements; horses with loose stool or fecal water and; horses needing to strengthen the intestinal lining to restore “leaky gut” to normal permeability levels.


Will Symbiotic help a horse with diarrhea?

There are many different causes of diarrhea (illness, infection, parasites, ulcers, sudden change in diet, etc).  Symbiotic helps address chronic diarrhea by colonizing the hindgut with beneficial bacteria to restore the proper balance of microflora. Symbiotic also increases nutrient absorption, keeps pathogens and bad bacteria at bay, eliminates mycotoxins, and reduces leaky gut and fecal water. Another often overlooked cause of diarrhea is inefficient or incomplete digestion in the stomach prior to food (usually processed feeds higher in sugar and starch) making its way to the colon. This is why it’s also important to focus on gastric health. Ulceraser encourages digestion in the foregut where it belongs rather than in the hindgut, which results in the release of volatile fatty acids and plummeting pH ultimately leading to the death of beneficial bacteria. Ulceraser is also hydrophilic, which means that it attracts and absorbs excess water (reducing diarrhea) as well. 


Do you offer farm incentive programs?

Yes.  For barns buying in bulk please email us at [email protected] to discuss eligibility and incentive structure.

Where do you ship from?

All orders ship from our warehouse in Wellington, FL.


Do you have sales or promo codes?

No. We do not have sales or promo codes because we offer the highest quality product at the lowest possible price year round.

Do you have sample sizes of the supplements?

No.  The reason we do not have sample sizes is because the average time frame for seeing an improvement is generally 2-3 weeks so for people wanting to sample the products we suggest starting with the 30 day supply.

We are longtime users of Equine Elixirs, and we’ve found that all of their products are palatable.

"Symbiotic has been a great addition to our program, particularly in the summer when we are traveling more with our horses. When things like hay or grass quality change on the road, we don’t notice gastric changes with our horses. Symbiotic has a lot to do with that. We are longtime users of Equine Elixirs, and we’ve found that all of their products are palatable. Our horses are happy to eat them. "

John French

Top Hunter Rider/Trainer
We have used Symbiotic for years and love the hindgut support it provides our horses during stressful times of showing, shipping and any other environmental changes.

"We have used Symbiotic for years and love the hindgut support it provides our horses during stressful times of showing, shipping and any other environmental changes. "

Lindsay Yinger

I have great results using Symbiotic for horses that previously had trouble managing stress while traveling and would develop an attitude.

"I have great results using Symbiotic for horses that previously had trouble managing stress while traveling and would develop an attitude. After introducing the pre/probiotic I’ve noticed much more pleasant attitudes in the horses and total ease with travel. "

Kerry McCahill

Young Horse Developer and Top Grand Prix Rider