Ulceraser™
Equine gastric support and ulcer prevention
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Equine gastric support and ulcer prevention

 

RESEARCH AND TESTING

The following ingredients have clinical research associated with them:

Arginine

Hinckley KA, Fearn S, Howard BR, Henderson IW. Nitric oxide donors as a treatment for grass induced acute laminitis in ponies. Equine Vet J. 1996 Jan;28(1):17-28.

Bryk J, Ochoa JB, Correia MI, et al. Effect of citrulline and glutamine on nitric oxide production in RAW 264.7 cells in an arginine-depleted environment. J Parenter Enteral Nutr. 2008 Jul-Aug;32(4):377-83.

Hayashi T, Juliet PA, Matsui-Hirai H, et al. l-Citrulline and l-arginine supplementation retards the progression of high-cholesteral-diet-induced atherosclerosis in rabbits. Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13681-6.

Copper

Gee E, Davies M, Firth E, et al. Osteochondrosis and copper: histology of articular cartilage from foals out of coppersupplemented and non-supplemented dams. Vet J. Jan;173(1):109-17.

Flax Seed

O'Neill W, McKee S, Clarke AF. Flaxseed (Linum usitatissimum) supplementation associated with reduced skin test lesional area in horses with Culicoides hypersensitivity. Can J Vet Res. Oct 2002;66(4):272-7.

Glycine

Zhong Z, Wheeler MD, Li X, et al. L-glycine: a novel antiinflammatory, immunomodulatory, and cytoprotective agent. Curr Opin Clin Nutri Metab Care. 2003 Mar;6(2):229-40.

Iron

Brommer H, Slet van Oldruitenborgh-Oosterbaan MM. Iron deficiency in stabled Dutch warmblood foals. J Vet Intern med. 2001 Sep-Oct;15(5):482-5.

Mullaney TP, Brown CM. Iron toxicity in neonatal foals. Equine Vet J. 1988 Mar;20(2):119-24.

Inoue Y, Matsui A, Asai Y, et al. Effect of exercise on iron metabolism in horses. Biol Trace Elem Res. 2005 Oct;107(1):33-42.

Lysine

Graham-Thiers PM, Kronfeld, DS. Amino acid supplemention improves muscle mass in aged and young horses. J Anim Sci. 2005 Dec;83(12):2783-8.

Graham PM, Ott EA, Brendemuhl JH, TenBroeck SH. The effect of supplemental lysine and threonine on growth and development of yearling horses. J Anim Sci. 1994 Feb;72(2):380-6.

Omega-3 Fatty Acids

Manhart DR, Scott BD, Gibbs PG, et al. Markers of inflammation in arthritic horses fed omega-3 fatty acids. Prof AnimSci. 2009;25:155-60.

Artemis P. Simopoulos, MD. Omega-3 fatty acids in inflammation and autoimmune diseases. 2002 Dec;21(6):495-505.

Neelley KA and Herthel DJ. Essential fatty acid supplementation as a preventative for carbohydrate overload-induced laminitis, in Proceedings. 43rd Annu Conv Am Assoc Equine Pract 1997;43:367-9.

L-Tryptophan

Noble GK, Brockwell YM, Munn KJ, et al. Effects of a commercial dose of l-tryptophan on plasma tryptophan concentrations and behaviour in horses. Equine Vet J. 2008 Jan;40(1):51-6.

 

 

EQUINE ANATOMY AND THE CAUSES OF ULCERS

Up to 90% of Performance Horses Have Ulcers


A horse’s stomach is divided into two parts. The lower region, which contains a mucus coating for protection from the gastric acid secreted, and the upper region, which lacks the thick mucosa prevalent below. Ulcers can occur in either part of the stomach, but occur most frequently in the upper portion because it lacks the protection found in the lower stomach.

Horses produce gastric acid 24 hours a day whether they are eating, sleeping or exercising. Without constant foraging, this acid irritates their stomach and intestinal lining.